Then & Now: Hereditary Angioedema
Emerging Science Fuels New Treatment Advances for Patients

No medications were approved in the U.S. specifically to treat HAE.

Several medications have been approved by the FDA in recent years to treat HAE by targeting the source of the disease.

Patients with HAE had limited options to relieve symptoms of an attack, and often were required to undergo invasive procedures to alleviate dangerous swelling.

Patients are able to self-administer new injectable medications at home to halt acute HAE attacks.

Scientists had little knowledge of the underlying cause of HAE.

New discoveries in the underlying cause of HAE have led to breakthroughs in both preventative and acute treatment options for patients.
As the condition is very rare, affecting 1 in 10,000 to 50,000 people, it is often under- or mis-diagnosed. Until recently, there were no treatments available to specifically treat HAE. A new report profiles the treatment gains that have been made over the last decade, as the underlying science behind HAE-induced inflammation has become clearer.